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1

Discovery of GS-9131: Design, synthesis and optimization of amidate prodrugs of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148

Richard L. Mackman, Adrian S. Ray, Hon C. Hui, Lijun Zhang, Gabriel Birkus, Constantine G. Boojamra, Manoj C. Desai, Janet L. Douglas, Ying Gao, Deborah Grant, Genevieve Laflamme, Kuei-Ying Lin, David

Journal:

Bioorganic & Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 430 KB

english, 2010

2

10.1097/00007632-200305150-00016

Klockner, Constantin, Valencia, Ray

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2003

3

Sagittal Alignment After Anterior Debridement and Fusion With or Without Additional Posterior Instrumentation in the Treatment of Pyogenic and Tuberculous Spondylodiscitis

Klöckner, Constantin, Valencia, Ray

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2003

4

Design, synthesis, and anti-HIV activity of 4′-modified carbocyclic nucleoside phosphonate reverse transcriptase inhibitors

Constantine G. Boojamra, Jay P. Parrish, David Sperandio, Ying Gao, Oleg V. Petrakovsky, Sharon K. Lee, David Y. Markevitch, Jennifer E. Vela, Genevieve Laflamme, James M. Chen, Adrian S. Ray, Abraham

Journal:

Bioorganic & Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 482 KB

english, 2009

5

Synthesis and anti-HIV activity of 2′-fluorine modified nucleoside phosphonates: Analogs of GS-9148

Richard L. Mackman, Kuei-Ying Lin, Constantine G. Boojamra, Hon Hui, Janet Douglas, Deborah Grant, Oleg Petrakovsky, Vidya Prasad, Adrian S. Ray, Tomas Cihlar

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2008

Langue:

english

Fichier:

PDF, 132 KB

english, 2008

6

Synthesis and anti-HIV activity of GS-9148 (2′-Fd4AP), a novel nucleoside phosphonate HIV reverse transcriptase inhibitor

Constantine G. Boojamra, Richard L. Mackman, David Y. Markevitch, Vidya Prasad, Adrian S. Ray, Janet Douglas, Deborah Grant, Choung U. Kim, Tomas Cihlar

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2008

Langue:

english

Fichier:

PDF, 137 KB

english, 2008

7

Laparoscopic management of gastric band erosions: a 10-year series of 49 cases

Geoffrey Paul Kohn, Cheryl Anne Hansen, Richard William Gilhome, Ray Charles McHenry, Dean Constantine Spilias, Chris Hensman

Journal:

Surgical Endoscopy

Année:

2012

Langue:

english

Fichier:

PDF, 328 KB

english, 2012

8

Low In Vitro Potential for Class-specific Toxicity of GS-9148, A Novel Nucleotide Reverse Transcriptase Inhibitor

Genevieve Laflamme, Constantin Boojamra, Lijun Zhang, Hon Hui, Robyn Fisher, Richard Mackman, Adrian Ray, Tomas Cihlar

Journal:

Antiviral Research

Année:

2008

Langue:

english

Fichier:

PDF, 72 KB

english, 2008

9

Tumor vaccines in 2010: Need for integration

David Koos, Steven F. Josephs, Doru T Alexandrescu, Ray Chun-Fai Chan, Famela Ramos, Vladimir Bogin, Vincent Gammill, Constantin A. Dasanu, Rosalia De Necochea-Campion, Neil H. Riordan, Ewa Carrier

Journal:

Cellular Immunology

Année:

2010

Langue:

english

Fichier:

PDF, 228 KB

english, 2010

10

A glider swing intervention for people with dementia

Mariah Snyder, Yueh-hsia Tseng, Cheryl Brandt, Catherine Croghan, Sandy Hanson, Ray Constantine, Leann Kirby

Journal:

Geriatric Nursing

Année:

2001

Langue:

english

Fichier:

PDF, 206 KB

english, 2001

11

Visualizing the Molecular Interactions of a Nucleotide Analog, GS-9148, with HIV-1 Reverse Transcriptase–DNA Complex

Eric B. Lansdon, Dharmaraj Samuel, Leanna Lagpacan, Katherine M. Brendza, Kirsten L. White, Magdeleine Hung, Xiaohong Liu, Constantine G. Boojamra, Richard L. Mackman, Tomas Cihlar, Adrian S. Ray, Mar

Journal:

Journal of Molecular Biology

Année:

2010

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2010

12

Evaluation of 2′-α-fluorine modified nucleoside phosphonates as potential inhibitors of HCV polymerase

Parrish, Jay P., Lee, Sharon K., Boojamra, Constantine G., Hui, Hon, Babusis, Darius, Brown, Brandon, Shih, I-hung, Feng, Joy Y., Ray, Adrian S., Mackman, Richard L.

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2013

Langue:

english

Fichier:

PDF, 594 KB

english, 2013

13

P4-322: Exploring the pharmacology of BQCA, a highly selective allosteric M1 potentiator

Ma, Lei, Jacobson, Marlene A., Kreatsoulas, Constantine, Getty, Krista L., Seabrook, Guy R., Ray, William J.

Journal:

Alzheimer's & Dementia

Année:

2008

Langue:

english

Fichier:

PDF, 53 KB

english, 2008

14

SPIE Proceedings [SPIE SPIE Optical Engineering + Applications - San Diego, CA (Sunday 2 August 2009)] Optical Manufacturing and Testing VIII - Experimental investigation of the dimensions and quality of laser-drilled holes in metals

Stafe, Mihai, Burge, James H., Fähnle, Oliver W., Negutu, Constantin, Vladoiu, Ionut, Williamson, Ray, Ducariu, Adrian N., Popescu, Ion M.

Année:

2009

Langue:

english

Fichier:

PDF, 180 KB

english, 2009

15

SPIE Proceedings [SPIE Photonics West '97 - San Jose, CA (Saturday 8 February 1997)] Optoelectronic Interconnects and Packaging IV - Optoelectronic design of the simultaneous optical multiprocessor exchange bus (SOME-Bus)

Lindquist, Robert G., Kulick, Jeffrey H., Cohen, Will E., Gaede, Rhonda K., Wells, B. Earl, Abushagur, Mustafa A. G., Shen, Dashen, Katsinis, Constantine, Kowel, Stephen T., Chen, Ray T., Guilfoyle, P

Année:

1997

Langue:

english

Fichier:

PDF, 880 KB

english, 1997

16

Information content and analysis methods for Multi-Modal High-Throughput Biomedical Data

Ray, Bisakha, Henaff, Mikael, Ma, Sisi, Efstathiadis, Efstratios, Peskin, Eric R., Picone, Marco, Poli, Tito, Aliferis, Constantin F., Statnikov, Alexander

Journal:

Scientific Reports

Année:

2014

Langue:

english

Fichier:

PDF, 882 KB

english, 2014

17

Potential utility of FLAIR in MRI-negative Cushing’s disease

Chatain, Grégoire P., Patronas, Nicholas, Smirniotopoulos, James G., Piazza, Martin, Benzo, Sarah, Ray-Chaudhury, Abhik, Sharma, Susmeeta, Lodish, Maya, Nieman, Lynnette, Stratakis, Constantine A., Ch

Journal:

Journal of Neurosurgery

Année:

2017

Langue:

english

Fichier:

PDF, 4.41 MB

english, 2017

18

Prevalence of Campylobacter jejuni on Turkey Wings at the Supermarket Level

RAYES, HUSEIN M., GENIGEORGIS, CONSTANTIN A., FARVER, THOMAS B.

Journal:

Journal of Food Protection

Année:

1983

Langue:

english

Fichier:

PDF, 263 KB

english, 1983

19

Prevalence of Campylobacter jejuni on Turkey Wings at the Supermarket Level

RAYES, HUSEIN M., GENIGEORGIS, CONSTANTIN A., FARVER, THOMAS B.

Journal:

Journal of Food Protection

Année:

1983

Fichier:

PDF, 263 KB

1983